Study Design: Case control study Place and Duration of Study: The research was carried out in Tanzania at African Institute of Mathematical Science for six months. To estimate genetic and residual variance parameters that account phenotypic variation of the disease.
To identify possible SNPs associated to a particular disease using different computational tools based on LMM approaches. Aims: To discuss different LMM-based approaches applied in GWAS and software packages implementation and Classify different computational tools that applies LMM approaches according to their applicability and performance.